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Hasegawa, H.

Publications and source records attributed to Hasegawa, H..

2 recordsLinked to original sources

Self-body recognition through a mirror: Easing spatial-consistency requirements for rubber hand illusion

Typical experiments to induce the rubber hand illusion (RHI) require experimental participants to gaze at a fake hand while tactile stimuli are provided to both the fake and hidden actual hands in a synchronous manner. However, under such conditions, postural and apparent disagreement between a seen fake hand and hidden actual hand prevents illusory body ownership. Provided that humans recognize mirror images as copies of the real world in spite of their spatial uncertainties or incongruence, the sensory disagreement may be accepted in RHI settings if using a mirror to show a fake hand. The present study performed two experiments to reveal how self-body recognition of a fake hand feature via mirror affects the RHI. These experiments were conducted in an RHI environment involving voluntary hand movements to investigate not only body ownership but also agency. The first experiment (Experiment 1) examined whether illusory ownership of a fake hand seen in a mirror could be induced. Then, we examined whether the RHI using a mirror image allows disagreement in orientation between the rubber and actual hands (Experiment 2). Subjective evaluations using a RHI questionnaire demonstrated that evoked embodiment of the rubber hand was stronger in the presence of a mirror than in the absence of it (Experiment 1) and that participants experienced the RHI even if the actual and rubber hands were incongruent in terms of orientation (45 {degrees}; Experiment 2). No significant difference was found in the change of perceived finger location (proprioceptive drift) between these experiments. These findings suggest that the use of a mirror masks subtle spatial incongruency or degrades the contribution of visual cues for spatial recognition and facilitates multisensory integration for bodily illusions.

neuroscience

Neurofeedback linked suppression of subthalamic beta oscillations speeds up movement initialisation in Parkinsonian Patients

Enhanced beta oscillations (13-30 Hz) in the subthalamic nucleus (STN) have been associated with clinical impairment in Parkinsons disease (PD), such as rigidity and slowing of movement, with the suppression of STN beta activity through medication or deep brain stimulation correlating with improvement in these symptoms. Recent studies have also emphasized the importance of the time dynamics of the STN beta oscillations in the pathology of PD. An increased probability of prolonged beta bursts, defined as periods when beta band power exceeds a certain threshold, was more closely related to motor symptoms than average power; and the occurrence of beta bursts just before a go cue slows cued movements. Here we adopted a sequential neurofeedback-behaviour task paradigm to investigate whether patients with PD can learn to suppress pathological beta oscillations recorded from STN with neurofeedback training and whether the training improves the motor performance. Results from twelve patients showed that, compared with the control condition, the neurofeedback training led to reduced incidence and duration of beta bursts in the STN local field potential (LFP) and also reduced the synchrony between the STN LFP and cortical activities measured through EEG in the beta frequency band. The changes were accompanied by a reduced reaction time in cued movements. These results suggest that volitional suppression of beta bursts facilitated by neurofeedback training could help improve movement initialisation in Parkinsons disease.\n\nSignificance StatementOur study suggests that a neurofeedback paradigm which focuses on the time dynamics of the target neural signal can facilitate volitional suppression of pathological beta oscillations in the STN in Parkinsons disease. Neurofeedback training was accompanied by reduced reaction time in cued movements, but associated with increased tremor in tremulous patients. The results strengthen the link between subthalamic beta oscillations and motor impairment, and also suggest that different symptom-specific neural signals could be targeted to improve neuromodulation strategies, either through brain stimulation or neurofeedback training, for patients with tremor and bradykinesia-rigidity.

neuroscience