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bioRxiv · 10.1101/2025.03.31.645756

MotifPeeker: R package for benchmarking epigenomic profiling methods using motif enrichment as a key metric

Dash, H.·Roberts, T.·Weinert, M.·Skene, N.
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Abstract

MotifPeeker benchmarks epigenomic profiling methods targeting transcription factors (TFs) where no "gold standard" reference exists, using motif enrichment as a key metric. With minimal input, users can analyse their data in a single function and receive an intuitive HTML report. Availability and ImplementationMotifPeeker is available on Bioconductor ([≥] v3.21) at https://bioconductor.org/packages/MotifPeeker. The complete source code is available on GitHub at https://github.com/neurogenomics/MotifPeeker, with full documentation provided at https://neurogenomics.github.io/MotifPeeker. Additionally, the MotifPeeker Docker image is hosted on GitHub at https://github.com/neurogenomics/MotifPeeker/pkgs/container/motifpeeker.

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Dash, H., Roberts, T., Weinert, M., Skene, N.. 2025-04-01. MotifPeeker: R package for benchmarking epigenomic profiling methods using motif enrichment as a key metric. https://doi.org/10.1101/2025.03.31.645756

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