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bioRxiv · 10.1101/2025.03.10.642298

Easy and interactive taxonomic profiling with Metabuli App

Lee, S.·Kim, J.·Mirdita, M.·Steinegger, M.
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Abstract

SummaryAccurate metagenomic taxonomic profiling is critical for understanding microbial communities. However, computational analysis often requires command-line proficiency and high-performance computing resources. To lower these barriers, we developed Metabuli App, an all-in-one desktop application that efficiently runs taxonomic profiling locally on a consumer-grade computer. It features user-friendly graphical interfaces for custom database curation, raw read quality control (QC), taxonomic profiling, and interactive result visualization. Availability and implementationGPLv3-licensed source code and prebuilt apps for Windows, macOS, and Linux are available at https://github.com/steineggerlab/Metabuli-App and are archived at https://doi.org/10.5281/zenodo.15876171. Analysis scripts are available at https://github.com/jaebeom-kim/metabuli-app-analysis. The Sankey-based taxonomy visualization component is available at https://github.com/steineggerlab/taxoview for easy integration into other web projects. Contactmartin.steinegger@snu.ac.kr

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Lee, S., Kim, J., Mirdita, M., Steinegger, M.. 2025-03-12. Easy and interactive taxonomic profiling with Metabuli App. https://doi.org/10.1101/2025.03.10.642298

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