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Mirdita, M.

Publications and source records attributed to Mirdita, M..

2 recordsLinked to original sources

MMseqs2 desktop and local web server app for fast, interactive sequence searches

The MMseqs2 desktop and web server app facilitates interactive sequence searches through custom protein sequence and profile databases on personal workstations. By eliminating MMseqs2s runtime overhead, we reduced response times to a few seconds at sensitivities close to BLAST.\n\nAvailability and implementationThe app is easy to install for non-experts. Source code, prebuilt desktop app packages for Windows, macOS and Linux, Docker images for the web server application, and a demo web server are available at https://search.mmseqs.com.\n\nContactmartin.steinegger@mpibpc.mpg.de or soeding@mpibpc.mpg.de

bioinformatics

Protein-level assembly increases protein sequence recovery from metagenomic samples manyfold

The open-source de-novo Protein-level assembler Plass (https://plass.mmseqs.org) assembles six-frame-translated sequencing reads into protein sequences. It recovers 2 to 10 times more protein sequences from complex metagenomes and can assemble huge datasets. We assembled two redundancy-filtered reference protein catalogs, 2 billion sequences from 640 soil samples (SRC) and 292 million sequences from 775 marine eukaryotic metatranscriptomes (MERC), the largest free collections of protein sequences.

bioinformatics