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bioRxiv · 10.1101/2024.08.25.609624

Proteome structuring of crown-of-thorns starfish

Zhu, Y.·Lu, Z.
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Abstract

This data report presents the proteome structuring of the crown-of-thorns starfish (COTS, Acanthaster planci) using the ColabFold system. The resulting dataset includes 31,743 predicted protein structures, covering 60.4% of residues with confident predictions and 35.5% with very high confidence. A preliminary structural bioinformatics analysis was conducted using post-AlphaFold methods, including fast structure clustering, ligand transplanting, and structure-based Gene Ontology (GO) annotation, which identified potential functions for previously uncharacterized proteins. These findings contribute to a deeper understanding of COTS biology and provide valuable data for developing biocontrol methods to mitigate the impact of COTS outbreaks on coral reefs.

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Zhu, Y., Lu, Z.. 2024-08-26. Proteome structuring of crown-of-thorns starfish. https://doi.org/10.1101/2024.08.25.609624

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