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bioRxiv · 10.1101/2021.08.15.456425

ColabFold - Making protein folding accessible to all

Mirdita, M.·Ovchinnikov, S.·Steinegger, M.
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Abstract

ColabFold offers accelerated protein structure and complex predictions by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFolds 40 - 60x faster search and optimized model use allows predicting close to a thousand structures per day on a server with one GPU. Coupled with Google Colaboratory, ColabFold becomes a free and accessible platform for protein folding. ColabFold is open-source software available at github.com/sokrypton/ColabFold. Its novel environmental databases are available at colabfold.mmseqs.com Contactmilot.mirdita@mpibpc.mpg.de, so@fas.harvard.edu, martin.steinegger@snu.ac.kr

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Mirdita, M., Ovchinnikov, S., Steinegger, M.. 2021-08-15. ColabFold - Making protein folding accessible to all. https://doi.org/10.1101/2021.08.15.456425

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