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bioRxiv · 10.1101/2021.03.05.433713

Zoonotic spillover of SARS-CoV-2: mink-adapted virus in humans

Rabalski, L.·Kosinski, M.·Mazur-Panasiuk, N.·Szewczyk, B.·Bienkowska-Szewczyk, K.·Kant, R.·Sironen, T.·Pyrc, K.·Grzybek, M.
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Abstract

The COVID-19 pandemic caused by SARS-CoV-2 started in fall 2019. A range of different mammalian species, including farmed mink, have been confirmed as susceptible to infection with this virus. We report here the spillover of mink-adapted SARS-CoV-2 from farmed mink to humans after extensive adaptation that lasted at least 3 months. We found the presence of four mutations in the S gene (that gave rise to variant: G75V, M177T, Y453F and C1247F) and others in an isolate obtained from SARS-CoV-2 positive patient.

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Rabalski, L., Kosinski, M., Mazur-Panasiuk, N., Szewczyk, B., Bienkowska-Szewczyk, K., Kant, R., Sironen, T., Pyrc, K., Grzybek, M.. 2021-03-05. Zoonotic spillover of SARS-CoV-2: mink-adapted virus in humans. https://doi.org/10.1101/2021.03.05.433713

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