Biology subjects

Constantin, N. D.

Publications and source records attributed to Constantin, N. D..

2 recordsLinked to original sources

bioRxiv2024

dScaff - an automatic bioinformatics framework for scaffolding draft de novo assemblies based on reference genome data

Rapid evolution of long-read sequencing technologies requires accurate, fast and user-friendly genome assembly and scaffolding tools. In this article we present Digital Scaffolding (dScaff), a bioinformatics tool that performs scaffolding of de novo genome assemblies based on reference scaffolds or chromosomes. dScaff makes use of a series of bash and R scripts in order to create a minimal complete scaffold from a genome assembly, with future features to be implemented. Herein, we demonstrate the functionality of dScaff on a novel genome assembly pertaining to a recently sequenced local strain of Drosophila suzukii.

bioinformatics↗

bioRxiv2022

A bioinformatics pipeline for the assessment of the evolutionary relationship of some Drosophila species based on class II transposons mapping

Transposons are mobile DNA sequences, known for their ability to insert into other locations in the genome. Genome sequencing allowed the identification of the high content of transposons in various model organisms. Here, we present a bioinformatics pipeline developed to estimate the evolutionary relationship between Drosophila melanogaster and other Drosophilidae based on the comparative analysis of the presence and distribution of class II transposons. Our study reveals that the presence and distribution of transposons hobo, HB, Tc1, Tc1-2, hopper and Bari1 points to close evolutionary relationship among D. melanogaster, D. simulans, D. sechellia and D. yakuba, which is in accordance with other data available in literature.

bioinformatics↗