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bioRxiv · 10.64898/2026.10.21.760778

NuFold RNA Structure Database: Large-Scale RNA Tertiary Structure Prediction with Confidence Metrics

Platt, D.·Kagaya, Y.·Kihara, D.
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Abstract

Summary: To bridge the gap between rapid RNA sequence discovery and slow experimental characterization, we present the NuFold RNA Structure Database (https://nufold.kiharalab.org/), a resource providing large-scale, precomputed full-atom RNA tertiary structures. By removing the computational barriers associated with running the method locally, this database makes high-accuracy RNA structure models readily accessible to the biological research community for a wide range of applications. Availability and implementation: All predicted structures and corresponding data are available at https://nufold.kiharalab.org/. The source code for the NuFold program is available at https://github.com/kiharalab/NuFold. Supplementary Information: For more insight into resulting statistics gathered for this project, see https://nufold.kiharalab.org/statistics. For more insight into how to utilize the webserver itself, see https://nufold.kiharalab.org/faq and https://nufold.kiharalab.org/tutorial.

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Platt, D., Kagaya, Y., Kihara, D.. 2026-10-22. NuFold RNA Structure Database: Large-Scale RNA Tertiary Structure Prediction with Confidence Metrics. https://doi.org/10.64898/2026.10.21.760778

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