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bioRxiv · 10.64898/2026.06.07.729490

STN-DBS frequency-tuned beta subband dynamics are associated with speech tempo in Parkinson's disease

Tian, H.·Wu, Y.·Fan, Y.·Yin, Z.·Guo, Y.·Meng, F.·Zhang, J.·Yu, H.·Li, L.
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Abstract

In Parkinsons disease, subthalamic nucleus deep brain stimulation (STN-DBS) frequency modulates narrow beta subbands, with low-frequency stimulation (LFS) selectively attenuating 15-23 Hz power. The negative association between this subband and speech tempo, together with the LFS-related improvement in articulatory rate, suggests that 15-23 Hz subband dynamics may serve as a candidate neural marker associated with speech tempo modulation.

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Tian, H., Wu, Y., Fan, Y., Yin, Z., Guo, Y., Meng, F., Zhang, J., Yu, H., Li, L.. 2026-06-10. STN-DBS frequency-tuned beta subband dynamics are associated with speech tempo in Parkinson's disease. https://doi.org/10.64898/2026.06.07.729490

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