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bioRxiv · 10.64898/2026.05.27.728128

Cyclic voltammetry electropolymerization of PEDOT: Polydopamine on gold electrodes

Saghir, S.·Schiavone, G.
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Abstract

This work presents a facile and rapid fabrication method for high-performance bioelectrode coatings through electropolymerization of poly(3,4-ethylenedioxythiophene) (PEDOT) and polydopamine (PDA). Expanding on previous work, we develop a cyclic voltammetry electropolymerization process to deposit PEDOT:PDA coatings on 2 mm gold electrode substrates. The coatings exhibit a 40-fold increase in cathodic charge storage capacity (~ 40mC{middle dot}cm-2) and significant impedance modulus reduction compared to uncoated gold electrodes. Morphological characterization revealed a uniformly porous surface that corroborates the enhancement in electrochemical performance. Our scalable approach offers a promising option to fabricate bioelectrodes for application to neural interfaces and implantable and wearable bioelectronics. Clinical RelevanceThe improved electrochemical performance and scalable fabrication of PEDOT:PDA coatings support their potential to enhance the stability and signal quality of neural and implantable bioelectronic devices.

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Saghir, S., Schiavone, G.. 2026-05-30. Cyclic voltammetry electropolymerization of PEDOT: Polydopamine on gold electrodes. https://doi.org/10.64898/2026.05.27.728128

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