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bioRxiv · 10.1101/829333

MoBPS - Modular Breeding Program Simulator

Pook, T.·Schlather, M.·Simianer, H.
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Abstract

The R-package MoBPS provides a computationally efficient and flexible framework to simulate complex breeding programs and compare their economic and genetic impact. Simulations are performed on the base of individuals and haplotypes are calculated on-the-fly by only saving founder haplotypes, points of recombination and mutations. MoBPS utilizes a highly efficient implementation with bit-wise storage of data and matrix multiplications from the associated R-package miraculix allowing to handle large scale populations. The modular structure of MoBPS allows to combine rather coarse simulations, as needed to generate founder populations, with a very detailed modeling of todays complex breeding programs, making use of all available biotechnologies. MoBPS provides pre-implemented functions for common breeding practices such as optimum genetic contributions and single-step GBLUP but also allows the user to replace certain steps with personalized and/or self-written solutions.

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Pook, T., Schlather, M., Simianer, H.. 2019-11-06. MoBPS - Modular Breeding Program Simulator. https://doi.org/10.1101/829333

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