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bioRxiv · 10.1101/768622

Diverse flanking sequence types of blaNDM in IncX3 and IncB/O/K/Z plasmids in Escherichia coli isolated from poultry

Zhu, J.·Cai, R.-M.·Zhang, L.-J.·Zheng, X.-R.·Lu, Y.-W.·Zhao, Q.-Y.·Chang, M.-X.·Jiang, H.
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Abstract

We identified 33 blaNDM-harboring Escherichia coli in 470 poultry samples from Shandong and Guangdong provinces during 2016 to 2017 and included the subtypes blaNDM-1, blaNDM-5 and blaNDM-9. The blaNDM gene possessed by all strains was plasmid-borne and ranged in size from 46 to 265 kb. The plasmids included the replicon types IncX3, IncY, IncB/O/K/Z and IncHI2 and most were transferable and stable in recipient host bacteria. Sequences flanking blaNDM in IncX3 and IncB/O/K/Z plasmids were diverse and the mobile element IS26 played an important role in the evolution of the IncB/O/K/Z blaNDM plasmids.

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Zhu, J., Cai, R.-M., Zhang, L.-J., Zheng, X.-R., Lu, Y.-W., Zhao, Q.-Y., Chang, M.-X., Jiang, H.. 2019-09-14. Diverse flanking sequence types of blaNDM in IncX3 and IncB/O/K/Z plasmids in Escherichia coli isolated from poultry. https://doi.org/10.1101/768622

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