Drug related and psychopathological symptoms in HIV-positive men who have sex with men who inject drugs during sex (Slamsex): Data from the U-SEX GESIDA 9416 Study.

Dolengevich-Segal, H.; Gonzalez-Baeza, A.; Valencia, J.; Valencia-Ortega, E.; Cabello, A.; Tellez-Molina, M. J.; Perez-Elias, M. J.; Serrano, R.; Perez-Latorre, L.; Martin-Carbonero, L.; Arponen, S.; Sanz-Moreno, J.; De la Fuente, S.; Bisbal, O.; Santos, I.; Casado, J. L.; Troya, J.; Cervero-Jimenez, M.; Nistal, S.; Cuevas, G.; Correas-Lauffer, J.; Torrens, M.; Ryan, P.; The USEX-Gesida Group,

doi:10.1101/703272

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bioRxiv · 10.1101/703272

Drug related and psychopathological symptoms in HIV-positive men who have sex with men who inject drugs during sex (Slamsex): Data from the U-SEX GESIDA 9416 Study.

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Abstract

ObjectivesIntravenous sexualized drug use also known as slamsex seems to be increasing among HIV-positive men who have sex with men (MSM). This practice may entail severe consequences for physical and mental health in this population. Research on the subject is scarce. The aim of our study was to describe the psychopathological background of a sample of HIV positive MSM who practiced slamsex during the previous year and compare the physical and psychological symptoms between these participants and those who practiced sexualized drug use (SDU) or chemsex without slamsex.\n\nDesign and MethodsParticipants (HIV-positive MSM) were recruited from the U-Sex study in 22 HIV clinics in Madrid during 2016-17. All participants completed an anonymous cross-sectional survey on sexual behaviour and recreational drug use. The present analysis is based on HIV-positive MSM who had practiced SDU.\n\nResultsThe survey sample comprised 742 participants. Of all the participants who completed the survey, 216 (29.1%) practiced chemsex, and of these, 34 (15.7%) had practiced slamsex. Participants who practiced slamsex were more likely to have current psychopathology (depression, anxiety and drug related disorders) than chemsex users. In addition, participants who practiced slamsex had more high-risk sexual behaviours, polydrug use and were more often diagnosed with sexually transmitted infections (STIs) and hepatitis C than those who did not inject drugs. Compared with patients who did not inject drugs, patients who engaged in slamsex showed more severe drug related symptoms (withdrawal and dependence), symptoms of severe intoxication (loss of consciousness), and severe psychopathological symptoms related to SDU, such as paranoid thoughts and suicidal behaviour.\n\nConclusionSlamsex (intravenous SDU) is closely associated with current psychiatric disorders and severe drug-related and psychiatric symptoms.

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Dolengevich-Segal, H., Gonzalez-Baeza, A., Valencia, J., Valencia-Ortega, E., Cabello, A., Tellez-Molina, M. J., Perez-Elias, M. J., Serrano, R., Perez-Latorre, L., Martin-Carbonero, L., Arponen, S., Sanz-Moreno, J., De la Fuente, S., Bisbal, O., Santos, I., Casado, J. L., Troya, J., Cervero-Jimenez, M., Nistal, S., Cuevas, G., Correas-Lauffer, J., Torrens, M., Ryan, P., The USEX-Gesida Group,. 2019-07-15. Drug related and psychopathological symptoms in HIV-positive men who have sex with men who inject drugs during sex (Slamsex): Data from the U-SEX GESIDA 9416 Study.. https://doi.org/10.1101/703272

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