Response to \"Expression reduction of biallelically transcribed X-linked genes during the female human preimplantation development.\"

Moreira de Mello, J. C.; Vibranovski, M. D.; Pereira, L. V.

doi:10.1101/701227

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bioRxiv · 10.1101/701227

Response to \"Expression reduction of biallelically transcribed X-linked genes during the female human preimplantation development.\"

Moreira de Mello, J. C.·Vibranovski, M. D.·Pereira, L. V.

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Abstract

Reinius and Sandberg (2019) have recently shown that X-linked balletic gene expression decreases during human preimplantation embryonic development, corroborating their previous hypothesis of X dampening as a mechanism of dosage compensation. Here we demonstrate that their analyses are based on biologically false premises, thus not demonstrating the phenomena of X dampening in humans.

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Moreira de Mello, J. C., Vibranovski, M. D., Pereira, L. V.. 2019-07-18. Response to \"Expression reduction of biallelically transcribed X-linked genes during the female human preimplantation development.\". https://doi.org/10.1101/701227

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