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bioRxiv · 10.1101/697524

Phased diploid genome assemblies for three strains of Candida albicans from oak trees

Hamlin, J. A. P.·Dias, G.·Bergman, C. M.·Bensasson, D.
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Abstract

Although normally a harmless commensal, Candida albicans has the potential to generate a wide range of infections including systemic candidaemia, making it the most common cause of bloodstream infections worldwide with a high rate of mortality. C. albicans has long been considered an obligate commensal, however, recent studies suggest it can live outside animal hosts. Here, we have generated PacBio sequencing and phased genome assemblies for three C. albicans strains from oak trees in the United Kingdom (NCYC 4144, NCYC 4145, and NCYC 4146). Our results provide phased de novo diploid assemblies for C. albicans and provide a framework to study patterns of genomic variation within and among strains of an important fungal pathogen.

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Hamlin, J. A. P., Dias, G., Bergman, C. M., Bensasson, D.. 2019-07-11. Phased diploid genome assemblies for three strains of Candida albicans from oak trees. https://doi.org/10.1101/697524

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