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bioRxiv · 10.1101/624759

Photoreceptor inputs into pupil control

Spitschan, M.
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Abstract

The size of the pupil depends on light level. Watson & Yellott (2012) developed a unified formula to predict pupil size from luminance, field diameter, age, and number of eyes. Luminance reflects input from the L and M cones in the retina but ignores the contribution of intrinsically photosensitive retinal ganglion cells (ipRGCs) expressing the photopigment melanopsin, which are known to control the size of the pupil. We discuss the role of melanopsin in controlling pupil size by reanalysing an extant data set. We confirm that melanopsin-weighted quantities, in conjunction with Watson & Yellotts formula, adequately model intensity-dependent pupil size. We discuss the contributions of other photoreceptors into pupil control.

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Spitschan, M.. 2019-05-07. Photoreceptor inputs into pupil control. https://doi.org/10.1101/624759

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