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bioRxiv · 10.1101/595892

Primary pterygium was not associated with corneal endothelial cell decrease in a rural Chinese population

Hu, Y.·Li, L.·Qi, W.·Liu, Z.·Liu, Y.·Yuan, L.
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Abstract

PurposeTo investigate the corneal endothelial cell density (ECD) in eyes with primary pterygium.\n\nMethodsWe first conducted a retrospective study to compare the ECD between 1670 eyes with primary pterygium and 4060 eyes without pterygium. Then we designed a prospective study to confirm the critical findings of the retrospective study in 95 patients with unilateral primary pterygium.\n\nResultsIn the retrospective study, the mean preoperative ECD in eyes with primary ptergyium (2453{+/-}306 cells/mm2) was statistically significantly lower than those in eyes without pterygium (2529{+/-}313 cells/mm2, P<0.0001). However, the difference was minor (76 cells/mm2, 3.1%). In the prospective study, the mean ECD in eyes with unilateral primary pterygium (2480{+/-}263 cells/mm2) was not significantly different from those in the contralateral eyes (2527{+/-}277 cells/mm2, P=0.20). The hexagonality (P=0.10) or coefficient of variation of size (P=0.15) of corneal endothelial cells was not significantly different between eyes with pterygium and the contralateral eyes.\n\nConclusionPrimary pterygium may not be associated with ECD decrease in our study cohort.

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Hu, Y., Li, L., Qi, W., Liu, Z., Liu, Y., Yuan, L.. 2019-04-02. Primary pterygium was not associated with corneal endothelial cell decrease in a rural Chinese population. https://doi.org/10.1101/595892

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