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bioRxiv · 10.1101/592014

Damage to the Right Insula Disrupts the Perception of Affective Touch

Kirsch, L. P.·Besharati, S.·Papadaki, C.·Crucianelli, L.·Bertagnoli, S.·Ward, N.·Moro, V.·Jenkinson, P. M.·Fotopoulou, A.
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Abstract

Specific, peripheral C-tactile afferents contribute to the perception of tactile pleasure, but the brain areas involved in their processing remain debated. We report the first human lesion study on the perception of C-tactile touch (N = 59), revealing that posterior and anterior right insula lesions reduce tactile, contralateral and ipsilateral pleasantness sensitivity, respectively. These findings are consistent with a posterior-to-anterior pattern of integration of interoceptive information in the frontoinsular junction.

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Kirsch, L. P., Besharati, S., Papadaki, C., Crucianelli, L., Bertagnoli, S., Ward, N., Moro, V., Jenkinson, P. M., Fotopoulou, A.. 2019-03-28. Damage to the Right Insula Disrupts the Perception of Affective Touch. https://doi.org/10.1101/592014

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