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bioRxiv · 10.1101/492645

Structure of a cytochrome-based bacterial nanowire

Filman, D. J.·Marino, S. F.·Ward, J. E.·Yang, L.·Mester, Z.·Bullitt, E.·Lovley, D. R.·Strauss, M.
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Abstract

Electrically conductive pili from Geobacter species, termed bacterial \"nanowires\", are intensely studied for their biological significance and potential in the development of new materials. We have characterized a unique nanowire from conductive G. sulfurreducens pili preparations by cryo-electron microscopy composed solely of the c-type cytochrome OmcS. We present here, at 3.4 [A] resolution, a novel structure of a cytochrome-based filament and discuss its possible role in long-range biological electron transport.\n\nSummary sentenceCryo-electron microscopy reveals the remarkable assembly of a c-type cytochrome into filaments comprising a heme-based bacterial nanowire.

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Filman, D. J., Marino, S. F., Ward, J. E., Yang, L., Mester, Z., Bullitt, E., Lovley, D. R., Strauss, M.. 2018-12-10. Structure of a cytochrome-based bacterial nanowire. https://doi.org/10.1101/492645

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