Benchmarking university medical centres for responsible metrics. A cross sectional study on timely results dissemination across 36 German centres

Wieschowski, S.; Riedel, N.; Wollmann, K.; Kahrass, H.; Mueller-Ohlraun, S.; Schuermann, C.; Kelley, S.; Kszuk, U.; Siegerink, B.; Dirnagl, U.; Meerpohl, J.; Strech, D.

doi:10.1101/467746

bioRxiv · 10.1101/467746

Benchmarking university medical centres for responsible metrics. A cross sectional study on timely results dissemination across 36 German centres

Wieschowski, S.·Riedel, N.·Wollmann, K.·Kahrass, H.·Mueller-Ohlraun, S.·Schuermann, C.·Kelley, S.·Kszuk, U.·Siegerink, B.·Dirnagl, U.·Meerpohl, J.·Strech, D.

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Abstract

ObjectiveTimely and comprehensive reporting of clinical trial results build the backbone of evidence-based medicine and responsible research. The proportion of timely disseminated trial results can inform alternative national and international benchmarking of university medical centers (UMCs).\n\nStudy Design and SettingFor all German UMCs we tracked all registered trials completed between 2009 and 2013. The results and an interactive website benchmark German UMCs regarding their performance in results dissemination.\n\nResultsWe identified and tracked 2,132 clinical trials. For 1,509 trials, one of the German UMCs took the academic lead. Of these 1,509 \"lead trials\", 39% published their results (mostly via journal publications) in a timely manner (<24 months after completion). More than six years after study completion, 26% of all eligible lead trials still had not disseminated results.\n\nConclusionDespite substantial attention from many stakeholders to the topic, there is still a strong delay or even absence of results dissemination for many trials. German UMCs have several opportunities to improve this situation. Further research should evaluate whether and how a transparent benchmarking of UMC performance in results dissemination helps to increase value and reduce waste in medical research.

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Wieschowski, S., Riedel, N., Wollmann, K., Kahrass, H., Mueller-Ohlraun, S., Schuermann, C., Kelley, S., Kszuk, U., Siegerink, B., Dirnagl, U., Meerpohl, J., Strech, D.. 2018-11-18. Benchmarking university medical centres for responsible metrics. A cross sectional study on timely results dissemination across 36 German centres. https://doi.org/10.1101/467746

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