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bioRxiv · 10.1101/417998

Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry

Lau, A. M. C.·Ahdash, Z.·Martens, C.·Politis, A.
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Abstract

SummaryHydrogen deuterium exchange-mass spectrometry (HDX-MS) has emerged as a powerful technique for interrogating the conformational dynamics of proteins and their complexes. Currently, analysis of HDX-MS data remains a laborious procedure, mainly due to the lack of streamlined software to process the large datasets. We present Deuteros which is a standalone software designed to be coupled with Waters DynamX HDX data analysis software, allowing the rapid analysis and visualization of data from differential HDX-MS.\n\nAvailabilityDeuteros is open-source and can be downloaded from https://github.com/andymlau/Deuteros, under the Apache 2.0 license.\n\nImplementationwritten in MATLAB and supported on both Windows and MacOS. Requires the MATLAB runtime library.\n\nContactargyris.politis@kcl.ac.uk

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Lau, A. M. C., Ahdash, Z., Martens, C., Politis, A.. 2018-09-14. Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry. https://doi.org/10.1101/417998

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