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bioRxiv · 10.1101/372037

Neural signatures of classical conditioning during human sleep

Canales-Johnson, A. F.·Bekinschtein, T. A.·Arzi, A.
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Abstract

Recent evidence indicate that humans can learn entirely new information during sleep. To elucidate the neural dynamics underlying sleep-learning we investigated brain activity during auditory-olfactory discriminatory associative learning in human sleep. We found that learning-related delta and sigma neural changes are involved in early acquisition stages, when new associations are being formed. In contrast, learning-related theta activity emerged in later stages of the learning process, after tone-odour associations were already established. These findings suggest that learning new associations during sleep is signalled by a dynamic interplay between slow-waves, sigma and theta activity.

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Canales-Johnson, A. F., Bekinschtein, T. A., Arzi, A.. 2018-07-19. Neural signatures of classical conditioning during human sleep. https://doi.org/10.1101/372037

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