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bioRxiv · 10.1101/350876

Human primary motor cortex represents evidence for a perceptual decision before motor response

Abstract

In perceptual decision making the brain extracts and accumulates decision evidence from a stimulus over time and eventually makes a decision based on the accumulated evidence. Several characteristics of this process have been observed in human electrophysiological experiments, especially an average build-up of motor-related signals supposedly reflecting accumulated evidence, when averaged across trials. A more direct approach to investigate the representation of decision evidence in brain signals is to correlate the trial-to-trial fluctuations of a model-based prediction of evidence with the measured signals. We here report results for an experiment in which we applied this approach to human magnetoencephalographic recordings. These results consolidate a range of previous findings and suggest that decision evidence is processed in three consecutive phases in the human brain: In an early phase around 120 ms after the evidence became visible on the screen, in a transition phase around 180 ms and a plateau phase roughly from 300 to 500 ms. We located sources of evidence representations in these phases in early visual (early), parietal (transition) and motor (plateau) regions of the brain while signals in posterior cingulate cortex represented decision evidence in all three phases. These findings imply that parietal cortex is only transiently involved in the processing of decision evidence, that motor areas represent accumulated evidence throughout decision making and that posterior cingulate cortex may have a central role in processing and maintaining decision evidence.

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BibTeXRIS

Bitzer, S., Park, H., Maess, B., von Kriegstein, K., Kiebel, S.. 2018-06-19. Human primary motor cortex represents evidence for a perceptual decision before motor response. https://doi.org/10.1101/350876

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