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bioRxiv · 10.1101/349704

Z-score to evaluate the absolute quality of macromolecular models based on SAXS data

Guzenko, D.·Strelkov, S. V.
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Abstract

Small-angle X-ray scattering (SAXS) is a highly popular technique to assess the native three-dimensional structure of biological macromolecules in solution. Here we introduce a statistical criterion, Z-score, as a novel quality measure of SAXS-based structural models which positively correlates with data quality. We propose that, besides a goodness-of-fit (GOF) measure such as reduced {chi}2, the Z-score reflecting the ability of a given SAXS curve to differentiate between possible models should always be reported.

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Guzenko, D., Strelkov, S. V.. 2018-06-18. Z-score to evaluate the absolute quality of macromolecular models based on SAXS data. https://doi.org/10.1101/349704

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