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bioRxiv · 10.1101/261982

Example of Methylome Analysis with MethylIT using Cancer Datasets

Sanchez, R.
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Abstract

Methyl-IT, a novel methylome analysis procedure based on information thermodynamics and signal detection was recently released. Methylation analysis involves a signal detection problem, and the method was designed to discriminate methylation regulatory signal from background noise induced by thermal fluctuations. Methyl-IT enhances the resolution of genome methylation behavior to reveal network-associated responses, offering resolution of gene pathway influences not attainable with previous methods. Herein, an example of MethylIT application to the analysis of breast cancer methylomes is presented.

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Sanchez, R.. 2018-02-09. Example of Methylome Analysis with MethylIT using Cancer Datasets. https://doi.org/10.1101/261982

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