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bioRxiv · 10.1101/2025.08.27.672358

Integrative multi-omics analysis of dietary fibre-induced modulations in the composition and function of chicken caecal microbiota

Ahmad, A. A.·Watson, K.·Khattak, F.·Kurian, D.·Kline, R.·Guizard, S.·Glendinning, L.
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Abstract

BackgroundThe sustainability of poultry farming faces significant challenges due to rising feed costs and competition with human food sources. Dietary fibre offers a promising, cost-effective alternative due to its beneficial impact on gut health. We utilised a multi-omics approach to understand the influence of soluble inulin and insoluble cellulose dietary fibres on the composition and function of caecal microbiota in broilers. ResultsHigh inulin significantly altered caecal microbial composition and promoted broader microbial metabolic adaptations, while high cellulose had a minimal impact. ConclusionsThese findings will enhance our understanding of how various fibre types and quantities shape gut microbiota, ultimately leading to improved poultry performance.

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Ahmad, A. A., Watson, K., Khattak, F., Kurian, D., Kline, R., Guizard, S., Glendinning, L.. 2025-08-27. Integrative multi-omics analysis of dietary fibre-induced modulations in the composition and function of chicken caecal microbiota. https://doi.org/10.1101/2025.08.27.672358

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