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bioRxiv · 10.1101/2025.06.17.660217

Neuromechanical Simulation with NEURON and MuJoCo

Fietkiewicz, C.·Tran, L.·McDougal, R.·Jackson, C.·Quinn, R. D.·Chiel, H. J.·Thomas, P. J.
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Abstract

In computational neuroscience, simulation platforms generally do not have adequate tools to model the brain, body and environment simultaneously. We demonstrate a method for simulating neuromechanical models using a novel combination of widely used software platforms: NEURON and MuJoCo. Different neural models are used to control a realistic musculoskeletal model in both open-loop and closed-loop configurations. Three models are presented: (1) an open-loop model using simple spiking neurons from the NEURON model library; (2) an open-loop model using realistic, spiking motoneurons; and (3) a closed-loop central pattern generator with feedback from the physics engine.

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Fietkiewicz, C., Tran, L., McDougal, R., Jackson, C., Quinn, R. D., Chiel, H. J., Thomas, P. J.. 2025-06-26. Neuromechanical Simulation with NEURON and MuJoCo. https://doi.org/10.1101/2025.06.17.660217

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