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bioRxiv · 10.1101/2025.01.07.631103

Projecting neurons from lateral entorhinal cortex to basolateral amygdala mediate the encoding of incidental odor-taste associations

Gonzlez-Parra, J. A.·Acciai, V.·Vidal-Palencia, L.·Canela-Grimau, M.·Busquets Garcia, A.
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Abstract

Daily choices are determined by prior direct or indirect associations between low-salience cues and reinforcers. In this study, we used a mouse odor-taste sensory preconditioning task combined with genetic, intersectional and chemogenetic approaches to identify a novel brain circuit involved in mediated learning. We found that neuronal projections from the lateral entorhinal cortex to the basolateral amygdala are engaged during low-salience stimuli associations, which is essential for mediated learning formation.

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Gonzlez-Parra, J. A., Acciai, V., Vidal-Palencia, L., Canela-Grimau, M., Busquets Garcia, A.. 2025-01-07. Projecting neurons from lateral entorhinal cortex to basolateral amygdala mediate the encoding of incidental odor-taste associations. https://doi.org/10.1101/2025.01.07.631103

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