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bioRxiv · 10.1101/2024.11.28.625873

AlphaPulldown2 - A General Pipeline for High-Throughput Structural Modeling

Molodenskiy, D.·Maurer, V.·Yu, D.·Chojnowski, G.·Bienert, S.·Tauriello, G.·Gilep, K.·Schwede, T.·Kosinski, J.
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Abstract

AlphaPulldown2 streamlines protein structural modeling by automating workflows, improving code adaptability, and optimizing data management for large-scale applications. It introduces an automated Snakemake pipeline, compressed data storage, support for additional modeling backends like UniFold and AlphaLink2, and a range of other improvements. These upgrades make AlphaPulldown2 a versatile platform for predicting both binary interactions and complex multi-unit assemblies. AvailabilityAlphaPulldown2 is freely available at https://github.com/KosinskiLab/AlphaPulldown.

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Molodenskiy, D., Maurer, V., Yu, D., Chojnowski, G., Bienert, S., Tauriello, G., Gilep, K., Schwede, T., Kosinski, J.. 2024-12-03. AlphaPulldown2 - A General Pipeline for High-Throughput Structural Modeling. https://doi.org/10.1101/2024.11.28.625873

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