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bioRxiv · 10.1101/2024.10.19.619201

Mathematical modeling of the frozen zone dynamics: towards using thermal imagers in cryotherapy

Ivakhnenko, O. V.·Todrin, O. F.·Globa, V. Y.·Chyzh, M. O.·Kovalov, G. O.·Shevchenko, S. N.
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Abstract

Using thermal imaging for cryoablation and cryotherapy is a convenient technique but it does not allow for visualization of what is inside. We model thermal field distribution which can help relate surface thermal field images to in-depth temperature field dynamics that show freezing and thawing processes dynamics. We consider the spatio-temporal distribution of temperature using examples of hydrogel and living tissue subjected to a cryoprobe. Freezing in the hydrogel is compared with the measurements using visual morphometry. Such studies can be useful for comparing in-vitro and in-vivo thermal field dynamics and for estimating the correct timing for cryoapplication.

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Ivakhnenko, O. V., Todrin, O. F., Globa, V. Y., Chyzh, M. O., Kovalov, G. O., Shevchenko, S. N.. 2024-10-22. Mathematical modeling of the frozen zone dynamics: towards using thermal imagers in cryotherapy. https://doi.org/10.1101/2024.10.19.619201

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