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bioRxiv · 10.1101/2024.10.04.616448

Impact of JN.1 booster vaccination on neutralisation of SARS-CoV-2 variants KP.3.1.1 and XEC

Arora, P.·Happle, C.·Kempf, A.·Nehlmeier, I.·Stankov, M. V.·Dopfer-Jablonka, A.·Behrens, G. M. N.·Poehlmann, S.·Hoffmann, M.
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Abstract

The SARS-CoV-2 KP.3.1.1 lineage is currently the dominating lineage on several continents. In parallel, the XEC lineage, a recombinant of KS.1.1 and KP.3.3, is on track of becoming the next dominant lineage in Europe and North America. Here we performed a rapid virological characterisation of the XEC lineage and studied the impact of JN.1 mRNA booster vaccination on KP.3.1.1 and XEC neutralisation.

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Arora, P., Happle, C., Kempf, A., Nehlmeier, I., Stankov, M. V., Dopfer-Jablonka, A., Behrens, G. M. N., Poehlmann, S., Hoffmann, M.. 2024-10-04. Impact of JN.1 booster vaccination on neutralisation of SARS-CoV-2 variants KP.3.1.1 and XEC. https://doi.org/10.1101/2024.10.04.616448

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