Mesenchymal stem cell-derived extracellular vesicles alleviate imiquimod-induced psoriasis symptoms in a mouse disease model

Yi, Y.; Yan, Y.; Liu, G.; Cui, C.; Zhai, Y.; Xu, K.; He, X.

doi:10.1101/2024.09.10.612372

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bioRxiv · 10.1101/2024.09.10.612372

Mesenchymal stem cell-derived extracellular vesicles alleviate imiquimod-induced psoriasis symptoms in a mouse disease model

Yi, Y.·Yan, Y.·Liu, G.·Cui, C.·Zhai, Y.·Xu, K.·He, X.

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Abstract

Psoriasis is an immune mediated, chronic inflammatory skin disease. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have inherent immunomodulatory potency from their parental cells, the mesenchymal stem cells (MSCs). In this study, we revealed the application potential of MSC-EVs to alleviate psoriatic symptoms in imiquimod-induced psoriasis mouse model.

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Yi, Y., Yan, Y., Liu, G., Cui, C., Zhai, Y., Xu, K., He, X.. 2024-09-16. Mesenchymal stem cell-derived extracellular vesicles alleviate imiquimod-induced psoriasis symptoms in a mouse disease model. https://doi.org/10.1101/2024.09.10.612372

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