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bioRxiv · 10.1101/2024.08.21.609056

NeuroVar: An Open-source Tool for Gene Expression and Variation Data Visualization for Biomarkers of Neurological Diseases

Aribi, H. B.·Abassi, N.·Awe, O. I.
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Abstract

BackgroundThe expanding availability of large-scale genomic data and the growing interest in uncovering gene-disease associations call for efficient tools to visualize and evaluate gene expression and genetic variation data. MethodologyData collection involved filtering biomarkers related to multiple neurological diseases from the ClinGen database. We developed a comprehensive pipeline that was implemented as an interactive Shiny application and a standalone desktop application. ResultsNeuroVar is a tool for visualizing genetic variation (single nucleotide polymorphisms and insertions/deletions) and gene expression profiles of biomarkers of neurological diseases. ConclusionThe tool provides a user-friendly graphical user interface to visualize genomic data and is freely accessible on the projects GitHub repository (https://github.com/omicscodeathon/neurovar).

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Aribi, H. B., Abassi, N., Awe, O. I.. 2024-08-22. NeuroVar: An Open-source Tool for Gene Expression and Variation Data Visualization for Biomarkers of Neurological Diseases. https://doi.org/10.1101/2024.08.21.609056

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