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bioRxiv · 10.1101/2024.08.07.607008

Hematophagy generates a convergent genomic signature in mosquitoes and sandflies

Devilliers, J.·Warren, B.·Rosato, E.·Kyriacou, C.·Feuda, R.
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Abstract

Blood-feeding (hematophagy) is widespread across Diptera (true flies), yet the underlying molecular mechanisms remain poorly understood. Using phylogenomics, we show that four gene families associated with neuro-modulation, immune responses, embryonic development, and iron metabolism have undergone independent expansions within mosquitoes and sandflies. Our findings illuminate the underlying genetic basis for blood-feeding adaptations in these important disease vectors.

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Devilliers, J., Warren, B., Rosato, E., Kyriacou, C., Feuda, R.. 2024-08-09. Hematophagy generates a convergent genomic signature in mosquitoes and sandflies. https://doi.org/10.1101/2024.08.07.607008

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