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bioRxiv · 10.1101/2024.06.11.598516

Deconvoluted methylation profiles discriminate between closely related melanocytic nevi

Aldea, D.·Macagno, N.·Marechal, E.·Moreno, M.·Romanet, P.·Pertuit, M.·Garcia, J.·Degardin, N.·Mallet, S.·James, I.·Captier, G.·Barlier, A.·Etchevers, H. C.
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Abstract

Congenital melanocytic nevi (CMN) and common acquired melanocytic nevi (AMN) are melanoma-predisposing skin conditions presenting excessive numbers of melanocytes but arising at different times in life. Appropriately weighted whole-genome methylation analysis can be used as a basis for further research in dermatopathology and as applied here provides new insights into nevus biology.

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Aldea, D., Macagno, N., Marechal, E., Moreno, M., Romanet, P., Pertuit, M., Garcia, J., Degardin, N., Mallet, S., James, I., Captier, G., Barlier, A., Etchevers, H. C.. 2024-06-14. Deconvoluted methylation profiles discriminate between closely related melanocytic nevi. https://doi.org/10.1101/2024.06.11.598516

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