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bioRxiv · 10.1101/2024.03.27.587092

Using absorbance detection for hs-SV-AUC characterization of adeno-association virus

Larson, N. R.·Bou-Assaf, G. M.·Laue, T. M.·Berkowitz, S. A.
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Abstract

Data are presented demonstrating that absorbance detection can be used during high-speed sedimentation velocity analytical ultracentrifugation (hs-SV-AUC) experiments to accurately characterize adeno-associated virus (AAV) drug products. Advantages and limitations of being able to use this detector in this specific type of SV-AUC experiment are discussed.

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Larson, N. R., Bou-Assaf, G. M., Laue, T. M., Berkowitz, S. A.. 2024-03-29. Using absorbance detection for hs-SV-AUC characterization of adeno-association virus. https://doi.org/10.1101/2024.03.27.587092

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