No evidence for the presence and control of tumor growth by cytoplasmic stress granules in pancreatic cancer

Libert, M.; Fain, J.; Bouchart, C.; Arsenijevic, T.; Van Laethem, J.-L.; Jacquemin, P.

doi:10.1101/2023.11.13.566518

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bioRxiv · 10.1101/2023.11.13.566518

No evidence for the presence and control of tumor growth by cytoplasmic stress granules in pancreatic cancer

Libert, M.·Fain, J.·Bouchart, C.·Arsenijevic, T.·Van Laethem, J.-L.·Jacquemin, P.

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Abstract

Cytoplasmic stress granules (SG) are attracting growing attention in cancer research1. As such, a study published in Cell2 has certainly served as a trigger for this trend which currently asserts that SG are a relevant therapeutic target. Here, we would like to express a warning about the conclusions of this article, as well as of the subsequent study3, and more generally on a methodological approach frequently used in research studying SG in cancer and which we believe to be misleading.

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Libert, M., Fain, J., Bouchart, C., Arsenijevic, T., Van Laethem, J.-L., Jacquemin, P.. 2023-11-15. No evidence for the presence and control of tumor growth by cytoplasmic stress granules in pancreatic cancer. https://doi.org/10.1101/2023.11.13.566518

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