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bioRxiv · 10.1101/2023.11.10.566529

Spatial Metabolomics co-registered with Multiplex Phenotyping for the Evaluation of Human Kidney Tissue

Zickuhr, G. M.·Um, I. H.·Laird, A.·Harrison, D. J.·Dickson, A. L.
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Abstract

A workflow has been evaluated that utilises a single tissue section to obtain spatially co-registered, molecular, and phenotypical information suitable for AI-enabled analysis. The impact of varying DESI-MSI conditions (e.g., temperature, scan rate, acquisition time) on the detection of small molecules and on tissue quality for integration into typical clinical pathology workflows assessed in human kidney.

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Zickuhr, G. M., Um, I. H., Laird, A., Harrison, D. J., Dickson, A. L.. 2023-11-15. Spatial Metabolomics co-registered with Multiplex Phenotyping for the Evaluation of Human Kidney Tissue. https://doi.org/10.1101/2023.11.10.566529

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