Characterization of the mitochondrial proteome in the ctenophore Mnemiopsis leidyi using MitoPredictor

Muthye, V. R.; Lavrov, D. V.

doi:10.1101/2023.08.23.554511

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bioRxiv · 10.1101/2023.08.23.554511

Characterization of the mitochondrial proteome in the ctenophore Mnemiopsis leidyi using MitoPredictor

Muthye, V. R.·Lavrov, D. V.

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Abstract

ii.Mitochondrial proteomes have been experimentally characterized for only a handful of animal species. However, the increasing availability of genomic and transcriptomic data allows one to infer mitochondrial proteins using computational tools. MitoPredictor is a novel random-forest classifier, which utilizes orthology-search, mitochondrial targeting signal (MTS) identification, and protein domain content to infer mitochondrial proteins in animals. MitoPredictors output also includes an easy-to-use R Shiny applet for the visualization and analysis of the results. In this article, we provide a guide for predicting and analyzing the mitochondrial proteome of the ctenophore Mnemiopsis leidyi using MitoPredictor.

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Muthye, V. R., Lavrov, D. V.. 2023-08-24. Characterization of the mitochondrial proteome in the ctenophore Mnemiopsis leidyi using MitoPredictor. https://doi.org/10.1101/2023.08.23.554511

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