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bioRxiv · 10.1101/2023.08.11.553001

AePUb promoter length modulates gene expression in Aedes aegypti

Anderson, M. A. E.·Leftwich, P. T.·Wilson, R.·Carabajal Paladino, L. Z.·Basu, S.·Rooney, S.·Adelman, Z.·Alphey, L.
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Abstract

Molecular tools for modulating transgene expression in Aedes aegypti are few. Here we demonstrate that adjustments to the AePUb promoter length can alter expression levels of two reporter proteins in Ae. aegypti cell culture and in mosquitoes. This provides a simple means for increasing or decreasing expression of a gene of interest and easy translation from cells to whole insects.

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Anderson, M. A. E., Leftwich, P. T., Wilson, R., Carabajal Paladino, L. Z., Basu, S., Rooney, S., Adelman, Z., Alphey, L.. 2023-08-11. AePUb promoter length modulates gene expression in Aedes aegypti. https://doi.org/10.1101/2023.08.11.553001

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