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bioRxiv · 10.1101/2023.08.11.552799

Stabilisation of the productive charge transfer states of coenzyme B12 in the photoreceptor protein, CarH

Camacho, I. S.·Wall, E.·Sazanovich, I. V.·Gozzard, E.·Towrie, M.·Hunt, N. T.·Hay, S.·Jones, A. R.
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Abstract

Time-resolved infrared spectroscopy reveals the flow of electron density through coenzyme B12 in the light-activated, bacterial transcriptional regulator, CarH. The protein stabilises a series of charge transfer states that result in a photoresponse that avoids reactive, and potentially damaging, radical photoproducts.

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Camacho, I. S., Wall, E., Sazanovich, I. V., Gozzard, E., Towrie, M., Hunt, N. T., Hay, S., Jones, A. R.. 2023-08-14. Stabilisation of the productive charge transfer states of coenzyme B12 in the photoreceptor protein, CarH. https://doi.org/10.1101/2023.08.11.552799

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