Multistability in neural systems with random cross-connections

Abstract

Neural circuits with multiple discrete attractor states could support a variety of cognitive tasks according to both empirical data and model simulations. We assess the conditions for such multistability in neural systems, using a firing-rate model framework, in which clusters of neurons with net self-excitation are represented as units, which interact with each other through random connections. We focus on conditions in which individual units lack sufficient self-excitation to become bistable on their own. Rather, multistability can arise via recurrent input from other units as a network effect for subsets of units, whose net input to each other when active is sufficiently positive to maintain such activity. In terms of the strength of within-unit self-excitation and standard-deviation of random cross-connections, the region of multistability depends on the firing-rate curve of units. Indeed, bistability can arise with zero self-excitation, purely through zero-mean random cross-connections, if the firing-rate curve rises supralinearly at low inputs from a value near zero at zero input. We simulate and analyze finite systems, showing that the probability of multistability can peak at intermediate system size, and connect with other literature analyzing similar systems in the infinite-size limit. We find regions of multistability with a bimodal distribution for the number of active units in a stable state. Finally, we find evidence for a log-normal distribution of sizes of attractor basins, which can appear as Zipfs Law when sampled as the proportion of trials within which random initial conditions lead to a particular stable state of the system.