Neural Mechanisms of Sequential Dependence in Time Perception: The Impact of Prior Task and Memory Processing

Abstract

Our perception and decision-making are susceptible to prior context. Such sequential dependence has been extensively studied in the visual domain, but less is known about its impact on time perception. Moreover, there are ongoing debates about whether these sequential biases occur at the perceptual stage or during subsequent post-perceptual processing. Using functional Magnetic Resonance Imaging (fMRI), we investigated neural mechanisms underlying temporal sequential dependence and the role of action in time judgments across trials. Participants performed a timing task where they had to remember the duration of green coherent motion and were cued to either actively reproduce its duration or simply view it passively. We found that sequential biases in time perception were only evident when the preceding task involved active duration reproduction. Merely encoding a prior duration without reproduction failed to induce such biases. Neurally, we observed activation in networks associated with timing, such as striato-thalamo-cortical circuits, and performance monitoring networks, particularly when a "Response" trial was anticipated. Importantly, the hippocampus showed sensitivity to these sequential biases, and its activation negatively correlated with the individuals sequential bias following active reproduction trials. These findings highlight the significant role of memory networks in shaping time-related sequential biases at the post-perceptual stages. Significance StatementOur study explores the neural mechanisms of sequential dependence in time perception and reveals that active reproduction of time duration in the previous trial can bias subsequent estimates, resulting in a sequential dependence effect. In contrast, passive viewing of a stimulus without reproducing its duration does not produce this effect. At the neural level, we observed increased activity in memory regions like the hippocampus when sequential biases were reduced. Furthermore, we found a negative correlation between hippocampal activation and sequential bias following active reproduction trials, suggesting that the involvement of memory networks mediates how we are influenced by past experiences when judging time.