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bioRxiv · 10.1101/2023.04.21.537877

CoSIA: an R Bioconductor package for CrOss Species Investigation and Analysis

Haldar, A. N.·Oza, V. H.·DeVoss, N. S.·Clark, A. D.·Lasseigne, B. N.
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Abstract

SummaryHigh throughput sequencing technologies have enabled cross-species comparative transcriptomic studies; however, there are numerous challenges for these studies due to biological and technical factors. We developed CoSIA (Cross-Species Investigation and Analysis), an Bioconductor R package and Shiny app that provides an alternative framework for cross-species transcriptomic comparison of non-diseased wild-type RNA sequencing gene expression data from Bgee across tissues and species (human, mouse, rat, zebrafish, fly, and nematode) through visualization of variability, diversity, and specificity metrics. Availability and Implementationhttps://github.com/lasseignelab/CoSIA ContactBrittany Lasseigne (bnp0001@uab.edu) Supplementary informationSee Supplementary Files

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Haldar, A. N., Oza, V. H., DeVoss, N. S., Clark, A. D., Lasseigne, B. N.. 2023-04-25. CoSIA: an R Bioconductor package for CrOss Species Investigation and Analysis. https://doi.org/10.1101/2023.04.21.537877

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