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bioRxiv · 10.1101/2022.10.06.511212

User-friendly high-content imaging analysis on a single desktop: R package H5CellProfiler

Wink, S.·Burger, G. B.·Le Devedec, S. E.·Beltman, J. B.·van de Water, B.
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Abstract

Technological development has led to ever-increasing amounts of data in high-content screening. For utilizing such data in an efficient, thorough, and user-friendly manner we developed the R package H5CellProfiler. H5CellProfiler is based on R packages data.table, ggvis, ggplot2 and shiny. H5CellProfiler launches a browser that allows scientists to analyze large single-cell datasets and make statistical summaries and graphs on their local desktop in a fast and memory-efficient manner. In addition, single-cell track labels are calculated and broken tracks are re-connected based on user-defined thresholds resulting in unique sets of annotated tracks.

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Wink, S., Burger, G. B., Le Devedec, S. E., Beltman, J. B., van de Water, B.. 2022-10-08. User-friendly high-content imaging analysis on a single desktop: R package H5CellProfiler. https://doi.org/10.1101/2022.10.06.511212

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