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bioRxiv · 10.1101/2022.08.30.505856

HADEG: A Curated Database of Hydrocarbon Aerobic Degradation Enzymes and Genes

Rojas-Vargas, J.·Castelan-Sanchez, H. G.·Pardo-Lopez, L.
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Abstract

Databases of genes and enzymes involved in hydrocarbon degradation have been previously reported. However, these databases specialize on only a specific group of hydrocarbons and/or are constructed partly based on enzyme sequences with putative functions indicated by in silico research, with no experimental evidence. Here, we present a curated database of Hydrocarbon Aerobic Degradation Enzymes and Genes (HADEG) containing proteins and genes involved in alkane, alkene, aromatic, and plastic aerobic degradation and biosurfactant production based solely on experimental evidence, which are present in bacteria, and fungi. HADEG includes 259 proteins for petroleum hydrocarbon degradation, 160 for plastic degradation, and 32 for biosurfactant production. This database will help identify and predict hydrocarbon degradation genes/pathways and biosurfactant production in genomes. Graphical abstract O_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=82 SRC="FIGDIR/small/505856v2_ufig1.gif" ALT="Figure 1"> View larger version (26K): org.highwire.dtl.DTLVardef@6019a4org.highwire.dtl.DTLVardef@1337dfaorg.highwire.dtl.DTLVardef@193b3fcorg.highwire.dtl.DTLVardef@d80de_HPS_FORMAT_FIGEXP M_FIG C_FIG Data summaryThe HADEG database repository is https://github.com/jarojasva/HADEG. All Supplementary Material file is available on: https://figshare.com/articles/dataset/Supplementary_Material_HADEG/20752642.

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Rojas-Vargas, J., Castelan-Sanchez, H. G., Pardo-Lopez, L.. 2022-09-01. HADEG: A Curated Database of Hydrocarbon Aerobic Degradation Enzymes and Genes. https://doi.org/10.1101/2022.08.30.505856

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