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bioRxiv · 10.1101/2022.07.22.501182

Polishing de novo nanopore assemblies of bacteria and eukaryotes with FMLRC2

Mak, Q. C.·Wick, R. R.·Holt, J. M.·Wang, J. R.
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Abstract

As accuracy and throughput of nanopore sequencing improves, it is increasingly common to perform long-read-first de novo genome assemblies followed by polishing with accurate short reads (Kim et al. 2021). We briefly introduce FMLRC2, the successor to the original FM-index Long Read Corrector (FMLRC), and illustrate its performance as a fast and accurate de novo assembly polisher for both microbial and eukaryotic genomes.

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Mak, Q. C., Wick, R. R., Holt, J. M., Wang, J. R.. 2022-07-23. Polishing de novo nanopore assemblies of bacteria and eukaryotes with FMLRC2. https://doi.org/10.1101/2022.07.22.501182

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