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bioRxiv · 10.1101/2022.07.07.499159

Energy-based Advection Modelling Using Bond Graphs

Gawthrop, P.·Pan, M.
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Abstract

Advection, the transport of a substance by the flow of a fluid, is a key process in biological systems. The energy-based bond graph approach to modelling chemical transformation within reaction networks is extended to include transport and thus advection. The approach is illustrated using a simple model of advection via circulating flow and by a simple pharmacokinetic model of anaesthetic gas uptake. This extension provides a physically-consistent framework for linking advective flows with the fluxes associated with chemical reactions within the context of physiological systems in general and the human physiome in particular.

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Gawthrop, P., Pan, M.. 2022-07-07. Energy-based Advection Modelling Using Bond Graphs. https://doi.org/10.1101/2022.07.07.499159

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