Re-introduction of endogenous pathways for propionyl-CoA, 1-propanol and propionate formation in Escherichia coli

Le, T.

doi:10.1101/2021.11.21.469472

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bioRxiv · 10.1101/2021.11.21.469472

Re-introduction of endogenous pathways for propionyl-CoA, 1-propanol and propionate formation in Escherichia coli

Le, T.

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Abstract

In a previous study, we found that 2-ketobutyrate (2-KB) was seriously degraded in Escherichia coli. In the present investigation, we tried to clarify the products of that degradation process, and intriguingly reconfirmed that 2-KB is chopped up to form propionyl-CoA, 1-propanol and propionate. This short commentary re-introduces efficient endogenous pathways for production of value-added odd-chain compounds such as propionyl-CoA-derived chemicals.

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Le, T.. 2021-11-22. Re-introduction of endogenous pathways for propionyl-CoA, 1-propanol and propionate formation in Escherichia coli. https://doi.org/10.1101/2021.11.21.469472

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